The dual endothelin-1 antagonist aprocitentan alleviates mitochondrial oxidative stress in human cardiac fibroblasts.

Authors :: Varzideh F
Jankauskas SS
Jain U
Soderquist L
Densu Agyapong E
Kansakar U
Santulli G
Source :: European heart journal. Cardiovascular pharmacotherapy [Eur Heart J Cardiovasc Pharmacother] 2024 Oct 04; Vol. 10 (6), pp. 566-568.
Publication Year :: 2024

Subjects :: Humans
Mitochondria, Heart drug effects
Mitochondria, Heart metabolism
Endothelin-1 metabolism
Cells, Cultured
Endothelin A Receptor Antagonists pharmacology
Endothelin Receptor Antagonists pharmacology
Oxidative Stress drug effects
Fibroblasts drug effects
Fibroblasts metabolism

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