Back to Search
Start Over
[Clinical studies on TMS-19-Q.O tablets, the preparation of a new macrolide antibiotic, in the field of oral surgery].
- Source :
-
The Japanese journal of antibiotics [Jpn J Antibiot] 1985 Mar; Vol. 38 (3), pp. 615-33. - Publication Year :
- 1985
-
Abstract
- Multicenter clinical trial or TMS-19-Q.O tablet was performed to evaluate the usefulness in oral surgery. The results obtained were as follows: Clinical efficacy was assessed by clinical points. The patients entered into the trial were 77 cases with periodontitis, 23 with pericoronitis, 92 with osteitis of jaw and 18 with other infections, and the each effective rates were 80.5, 60.9, 83.7 and 72.2%, respectively. Overall effective rate was 79.0%. Isolation frequency of organisms were 33.8% in periodontitis, 34.8% in osteitis of jaw and 17.4% in pericoronitis. Bacteria isolated were aerobic organisms (63.1%) and anaerobic organisms (36.9%). TMS-19-Q.O tablet was well tolerated, and no adverse reaction was observed.
- Subjects :
- Adolescent
Adult
Aged
Anti-Bacterial Agents administration & dosage
Clinical Trials as Topic
Female
Gingivitis drug therapy
Humans
Leucomycins administration & dosage
Male
Microbial Sensitivity Tests
Middle Aged
Streptococcus pyogenes isolation & purification
Tablets
Anti-Bacterial Agents therapeutic use
Jaw Diseases drug therapy
Leucomycins therapeutic use
Miocamycin analogs & derivatives
Periodontitis drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0368-2781
- Volume :
- 38
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Japanese journal of antibiotics
- Publication Type :
- Academic Journal
- Accession number :
- 3897602