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The use of venous blood gas in assessing arterial acid-base and oxygenation status - an analysis of aggregated data from multiple studies evaluating the venous to arterial conversion (v-TAC) method.
- Source :
-
Expert review of respiratory medicine [Expert Rev Respir Med] 2024 Jul; Vol. 18 (7), pp. 553-559. Date of Electronic Publication: 2024 Jul 15. - Publication Year :
- 2024
-
Abstract
- Background: Several methods exist to reduce the number of arterial blood gases (ABGs). One method, Roche v-TAC, has been evaluated in different patient groups. This paper aggregates data from these studies, in different patient categories using common analysis criteria.<br />Research Design and Methods: We included studies evaluating v-TAC based on paired arterial and peripheral venous blood samples. Bland-Altman analysis compared measured and calculated arterial values of pH, PCO <subscript>2</subscript> , and PO <subscript>2</subscript> . Subgroup analyses were performed for normal, chronic hypercapnia and chronic base excess, acute hyper- and hypocapnia, and acute and chronic base deficits.<br />Results: 811 samples from 12 studies were included. Bias and limits of agreement for measured and calculated values: pH 0.001 (-0.029 to 0.031), PCO <subscript>2</subscript> -0.08 (-0.65 to 0.49) kPa, and PO <subscript>2</subscript> 0.04 (-1.71 to 1.78) kPa, with similar values for all sub-group analyses.<br />Conclusion: These data suggest that v-TAC analysis may have a role in replacing ABGs, avoiding arterial puncture. Substantial data exist in patients with chronic hypercapnia and chronic base excess, acute hyper- and hypocapnia, and in patients with relatively normal acid-base status, with similar bias and precision across groups and across study data. Limited data exist for patients with acute and chronic base deficits.
- Subjects :
- Humans
Hydrogen-Ion Concentration
Carbon Dioxide blood
Acid-Base Equilibrium
Hypercapnia blood
Hypercapnia physiopathology
Hypercapnia diagnosis
Acid-Base Imbalance blood
Acid-Base Imbalance diagnosis
Acid-Base Imbalance physiopathology
Predictive Value of Tests
Blood Gas Analysis methods
Oxygen blood
Arteries physiopathology
Veins
Subjects
Details
- Language :
- English
- ISSN :
- 1747-6356
- Volume :
- 18
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Expert review of respiratory medicine
- Publication Type :
- Academic Journal
- Accession number :
- 38973767
- Full Text :
- https://doi.org/10.1080/17476348.2024.2378021