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Hydroxyurea in Sickle Cell Disease and Invasive Bacterial Infections: A Case-Control Study.

Authors :
Pascault A
Koehl B
Brousse V
Benkerrou M
Gaschignard J
Source :
Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2024 Sep 26; Vol. 13 (9), pp. 493-495.
Publication Year :
2024

Abstract

Hydroxyurea decreases painful events among children with sickle cell disease (SCD) but could increase the risk of infections in treated patients through leucopenia. We performed a case-control study, comparing hydroxyurea treatment for SCD in cases with an invasive bacterial infection and in controls without infection. No difference was found.<br /> (© The Author(s) 2024. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our siteā€”for further information please contact journals.permissions@oup.com.)

Details

Language :
English
ISSN :
2048-7207
Volume :
13
Issue :
9
Database :
MEDLINE
Journal :
Journal of the Pediatric Infectious Diseases Society
Publication Type :
Academic Journal
Accession number :
38970408
Full Text :
https://doi.org/10.1093/jpids/piae071