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Ethanol promotes protease activated receptor 1: Chemokine (C-X-C motif) receptor 4 heteromerization and enhances thrombin-induced impairment of human lung endothelial cell barrier function.
- Source :
-
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Oct; Vol. 1870 (7), pp. 167335. Date of Electronic Publication: 2024 Jul 03. - Publication Year :
- 2024
-
Abstract
- Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Matthias Majetschak reports financial support was provided by National Institutes of Health. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
- Subjects :
- Humans
Receptors, CXCR4 metabolism
Receptors, CXCR4 genetics
Protein Multimerization drug effects
Thrombin metabolism
Receptor, PAR-1 metabolism
Receptor, PAR-1 genetics
Endothelial Cells metabolism
Endothelial Cells drug effects
Lung metabolism
Lung pathology
Lung drug effects
Ethanol pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1879-260X
- Volume :
- 1870
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Biochimica et biophysica acta. Molecular basis of disease
- Publication Type :
- Academic Journal
- Accession number :
- 38969148
- Full Text :
- https://doi.org/10.1016/j.bbadis.2024.167335