Effect of Apixaban on Clinical Outcomes in Outpatients With COVID-19: The APOLLO Randomized Clinical Trial.

Competing Interests: Disclosures Dr de Barros e Silva reports research support and consulting fees from Pfizer, Bayer, and Roche Diagnostics. Dr Macedo reports consulting fees from Pfizer, Bayer, Novartis, Janssen, Sanofi, Daiichi-Sankyo, Zodiac, Astellas, Ferring, and Astra-Zeneca. Dr Lopes reports research grants or contracts from Amgen, Bristol Myers Squibb, GlaxoSmithKline, Medtronic, Pfizer, and Sanofi-Aventis; funding for educational activities or lectures from Pfizer, Bristol Myers Squibb, Novo Nordisk, and AstraZeneca; and funding for consulting from Bayer, Boehringer Ingelheim, Bristol Myers Squibb, Novo Nordisk, and AstraZeneca. Dr Cavalcanti reports grants from Bayer, Bactiguard, Johnson & Johnson, do Brasil, Hemaclear, Hillrom, and Pfizer. Dr Berwanger reports grants from AstraZeneca, Pfizer, Novartis, Servier, Bayer, Amgen, and Boehringer-Ingelheim. Dr Azevedo reports research support from Aché, consulting fees from Halex-Istar, and personal fees from Baxter. Dr Alexander reports research support from Bayer, Boehringer Ingelheim, Bristol Myers Squibb, CryoLife, CSL Behring, Ferring, GlaxoSmithKline, the US Food and Drug Administration, the US National Institutes of Health, and XaTek; and consulting fees or honoraria from AbbVie, Atricure, Bristol Myers Squibb, CryoLife, GlaxoSmithKline, Janssen, Pfizer, Portola, and the US VA CSP. Dr Avezum reports research grants from Bayer, EMS, Novartis, and Population Health Research Institute, and consulting fees from Bayer. Dr Ramacciotti reports speaker’s bureau participation for Bayer, BMS/PFE, Aspen, BI, and Daiichi Sankyo; and serving as a consultant or advisor for Pfizer, BMS, Bayer, Sanofi, Amgen, Daiichi-Sankyo, Cristalia, and Aspen. Drs Bronhara, Suiama, Antunes, de Aquino Martins, Ribeiro, de Moura Xavier de Moraes, Aguiar, Rosa, Veiga, Gebara, Damiani, Barbosa, Lopes, and Gonçalves report no disclosures.