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FOXP3 snatches transcription factors depending on the context.
- Source :
-
The Journal of experimental medicine [J Exp Med] 2024 Sep 02; Vol. 221 (9). Date of Electronic Publication: 2024 Jul 01. - Publication Year :
- 2024
-
Abstract
- FOXP3 hijacks DNA-binding proteins to regulate gene expression. In this issue of JEM, He et al. (https://doi.org/10.1084/jem.20232068) propose a dynamic model in which FOXP3 associates with DNA-binding proteins to regulate Treg cell function in response to environmental cues.<br /> (© 2024 Schmidleithner et al.)
- Subjects :
- Humans
Animals
Gene Expression Regulation
DNA-Binding Proteins metabolism
DNA-Binding Proteins genetics
Transcription Factors metabolism
Transcription Factors genetics
Forkhead Transcription Factors metabolism
Forkhead Transcription Factors genetics
T-Lymphocytes, Regulatory immunology
T-Lymphocytes, Regulatory metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 1540-9538
- Volume :
- 221
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- The Journal of experimental medicine
- Publication Type :
- Academic Journal
- Accession number :
- 38949640
- Full Text :
- https://doi.org/10.1084/jem.20240940