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Identification and management of interstitial lung disease associated with systemic sclerosis (SSc-ILD), rheumatoid arthritis (RA-ILD), and polymyositis/dermatomyositis (PM/DM-ILD): development of expert consensus-based clinical algorithms.
- Source :
-
Expert review of respiratory medicine [Expert Rev Respir Med] 2024 Jun; Vol. 18 (6), pp. 447-456. Date of Electronic Publication: 2024 Jul 15. - Publication Year :
- 2024
-
Abstract
- Background: Clinical guidance on the identification and management of connective tissue disease-associated interstitial lung disease (CTD-ILD) is needed for optimal clinical practice. We aimed to develop clinical algorithms for identifying and managing three common CTD-ILDs: those associated with systemic sclerosis (SSc-ILD), rheumatoid arthritis (RA-ILD), and polymyositis/dermatomyositis (PM/DM-ILD).<br />Research Design and Methods: Meetings were held October-November 2023 to create consensus-based algorithms for identifying and managing SSc-ILD, RA-ILD, and PM/DM-ILD in clinical practice, based on expert consensus statements for identification and management of CTD-ILD previously derived from a Delphi process.<br />Results: We developed clinical algorithms for SSc-ILD, RA-ILD, and PM/DM-ILD that highlight both commonalities and differences in the identification and management of these CTD-ILDs. Importantly, ILD should be suspected in patients with SSc, RA, or PM/DM who have respiratory symptoms. Chest high-resolution computed tomography has utility for screening, diagnosis and assessment of severity. Furthermore, regular follow-up and multidisciplinary management are important. Disease-specific considerations include unique risk factors such as anti-topoisomerase I antibodies in SSc-ILD, high-titer cyclic citrullinated peptide antibodies in RA, anti-aminoacyl tRNA synthetase antibodies in PM/DM, and anti-melanoma differentiation-associated gene 5 antibody in DM.<br />Conclusions: These algorithms may help physicians to identify and manage patients with SSc-ILD, RA-ILD, or PM/DM-ILD.
- Subjects :
- Humans
Lung Diseases, Interstitial diagnosis
Lung Diseases, Interstitial immunology
Lung Diseases, Interstitial therapy
Algorithms
Dermatomyositis immunology
Dermatomyositis diagnosis
Dermatomyositis complications
Dermatomyositis therapy
Scleroderma, Systemic complications
Scleroderma, Systemic diagnosis
Arthritis, Rheumatoid complications
Arthritis, Rheumatoid diagnosis
Consensus
Subjects
Details
- Language :
- English
- ISSN :
- 1747-6356
- Volume :
- 18
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Expert review of respiratory medicine
- Publication Type :
- Academic Journal
- Accession number :
- 38943279
- Full Text :
- https://doi.org/10.1080/17476348.2024.2374910