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Chemical constituents from the twigs with leaves of Tetradium trichotomum .
- Source :
-
Journal of Asian natural products research [J Asian Nat Prod Res] 2024 Nov; Vol. 26 (11), pp. 1285-1291. Date of Electronic Publication: 2024 Jun 26. - Publication Year :
- 2024
-
Abstract
- Twelve compounds, comprising of four new ones, 6 β ,7α-limondiol ( 1 ) and ethyl 19-hydroxyisoobacunoate diosphenol ( 2 ), N -benzoyl 3-prenyltyramine ( 9 ) and 9- O -methyl integrifoliodiol ( 12 ), were isolated from the twigs with leaves of Tetradium trichotomum . The structures were elucidated by analysis of MS, NMR, and single-crystal X-ray diffraction. Compounds 1 , 6 , 8 , 9 and 12 exhibited immunosuppressive activities in vitro against the proliferation of ConA-induced T lymphocytes and LPS-induced B cells.
- Subjects :
- Molecular Structure
Immunosuppressive Agents pharmacology
Immunosuppressive Agents chemistry
Immunosuppressive Agents isolation & purification
T-Lymphocytes drug effects
Animals
Drugs, Chinese Herbal chemistry
Drugs, Chinese Herbal pharmacology
Drugs, Chinese Herbal isolation & purification
Crystallography, X-Ray
Plant Leaves chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1477-2213
- Volume :
- 26
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Journal of Asian natural products research
- Publication Type :
- Academic Journal
- Accession number :
- 38920362
- Full Text :
- https://doi.org/10.1080/10286020.2024.2363403