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Hypercholesterolaemia treated with inclisiran.
- Source :
-
Ugeskrift for laeger [Ugeskr Laeger] 2024 Jun 10; Vol. 186 (24). Date of Electronic Publication: 2024 Jun 10. - Publication Year :
- 2024
-
Abstract
- In this case report, a 31-year-old woman with heterozygous familial hypercholesterolaemia (FH) underwent treatment with statins and PCSK9 inhibitor but had to discontinue due to elevated creatine kinase levels and neurological and muscular side effects. In 2021, the patient received inclisiran therapy, the first known instance of its application in Denmark. No side effects were reported, and LDL cholesterol levels were significantly reduced. This case report highlights the potential of inclisiran as an effective and well-tolerated treatment for individuals with heterozygous FH.<br /> (Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.)
- Subjects :
- Humans
Female
Adult
Cholesterol, LDL blood
Anticholesteremic Agents therapeutic use
Anticholesteremic Agents adverse effects
Hyperlipoproteinemia Type II drug therapy
PCSK9 Inhibitors
Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use
Hydroxymethylglutaryl-CoA Reductase Inhibitors adverse effects
Subjects
Details
- Language :
- Danish
- ISSN :
- 1603-6824
- Volume :
- 186
- Issue :
- 24
- Database :
- MEDLINE
- Journal :
- Ugeskrift for laeger
- Publication Type :
- Academic Journal
- Accession number :
- 38903035
- Full Text :
- https://doi.org/10.61409/V12230767