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Hypercholesterolaemia treated with inclisiran.

Authors :
Todorovac N
Hansen MS
Elpert FP
Source :
Ugeskrift for laeger [Ugeskr Laeger] 2024 Jun 10; Vol. 186 (24). Date of Electronic Publication: 2024 Jun 10.
Publication Year :
2024

Abstract

In this case report, a 31-year-old woman with heterozygous familial hypercholesterolaemia (FH) underwent treatment with statins and PCSK9 inhibitor but had to discontinue due to elevated creatine kinase levels and neurological and muscular side effects. In 2021, the patient received inclisiran therapy, the first known instance of its application in Denmark. No side effects were reported, and LDL cholesterol levels were significantly reduced. This case report highlights the potential of inclisiran as an effective and well-tolerated treatment for individuals with heterozygous FH.<br /> (Published under Open Access CC-BY-NC-BD 4.0. https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Details

Language :
Danish
ISSN :
1603-6824
Volume :
186
Issue :
24
Database :
MEDLINE
Journal :
Ugeskrift for laeger
Publication Type :
Academic Journal
Accession number :
38903035
Full Text :
https://doi.org/10.61409/V12230767