Secondary metabolites from the fungus Cladosporium xylophilum .

A new cladosporol derivative xylophilum A ( 1 ), together with 10 known compounds ( 2 - 11 ), were isolated from the rice fermentation of the fungus Cladosporium xylophilum . Their structures were established by extensive spectroscopic methods and comparison of their NMR data with literatures. The antimicrobial activity of compound 1 against 11 kinds of pathogenic microbial was evaluated, but no significant activity was found (MIC >100 μg/ml).