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Associations of nutrition impact symptoms with depression in patients with advanced cancer.

Authors :
Amano K
Okamura S
Matsuda Y
Baracos VE
Mori N
Miura T
Tatara R
Kessoku T
Tagami K
Otani H
Mori M
Taniyama T
Nakajima N
Nakanishi E
Kako J
Morita T
Miyashita M
Source :
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [Support Care Cancer] 2024 Jun 19; Vol. 32 (7), pp. 445. Date of Electronic Publication: 2024 Jun 19.
Publication Year :
2024

Abstract

Purpose: Advanced cancer patients have nutrition impact symptoms (NISs), while many of them have depressive moods. This study aimed to determine the associations of NISs with depression.<br />Methods: This study was a secondary analysis. The dietary intake and 19 NISs in patients receiving palliative care were evaluated using 10-point scales, and the patients were categorized into two groups (non-depression and depression groups) using the cutoff based on the Patient Health Questionnaire-9 (PHQ-9). To determine associations between depression and the number of NISs with a score of ≥ 4, the adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the logistic regression model were calculated.<br />Results: A total of 225 participants were divided into the non-depression group (n = 148) and the depression group (n = 77). The prevalence of depression was 34.2%. Dietary intake was lower, and the number of NISs with a score of ≥ 4 was higher in the depression group (both p < 0.001). All NISs were more severe in the depression group. Significant differences were observed in 15 of the 19 NISs. In the logistic regression model, significantly higher adjusted ORs were observed in the groups with 4-6 NISs and 7 or more NISs with a score of ≥ 4 (10.76 [95% CI, 2.07-55.91], p = 0.016; 17.02 [95% CI, 3.08-94.22], p < 0.001) than in the group with no NISs with a score of ≥ 4.<br />Conclusion: Having four or more NISs with a score ≥ 4 was associated with depression.<br /> (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)

Details

Language :
English
ISSN :
1433-7339
Volume :
32
Issue :
7
Database :
MEDLINE
Journal :
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Publication Type :
Academic Journal
Accession number :
38896133
Full Text :
https://doi.org/10.1007/s00520-024-08645-6