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What Can the Gut Microbiota of Animals Teach Us about the Relationship between Nutrition and Burden of Lifestyle Diseases?

Authors :
Mafra D
Borges NA
Baptista BG
Martins LF
Borland G
Shiels PG
Stenvinkel P
Source :
Nutrients [Nutrients] 2024 Jun 06; Vol. 16 (11). Date of Electronic Publication: 2024 Jun 06.
Publication Year :
2024

Abstract

The gut microbiota performs several crucial roles in a holobiont with its host, including immune regulation, nutrient absorption, synthesis, and defense against external pathogens, significantly influencing host physiology. Disruption of the gut microbiota has been linked to various chronic conditions, including cardiovascular, kidney, liver, respiratory, and intestinal diseases. Studying how animals adapt their gut microbiota across their life course at different life stages and under the dynamics of extreme environmental conditions can provide valuable insights from the natural world into how the microbiota modulates host biology, with a view to translating these into treatments or preventative measures for human diseases. By modulating the gut microbiota, opportunities to address many complications associated with chronic diseases appear. Such a biomimetic approach holds promise for exploring new strategies in healthcare and disease management.

Details

Language :
English
ISSN :
2072-6643
Volume :
16
Issue :
11
Database :
MEDLINE
Journal :
Nutrients
Publication Type :
Academic Journal
Accession number :
38892721
Full Text :
https://doi.org/10.3390/nu16111789