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Significant improvement of a nevus spilus-type congenital melanocytic nevus with oral selumetinib.
- Source :
-
Pediatric dermatology [Pediatr Dermatol] 2024 Sep-Oct; Vol. 41 (5), pp. 936-937. Date of Electronic Publication: 2024 Jun 17. - Publication Year :
- 2024
-
Abstract
- Giant congenital melanocytic nevi (GCMN) can be cosmetically significant and can lead to melanoma. There is no standard pharmacologic treatment for GCMN. We present the case of an 8-year-old female with kaposiform lymphangiomatosis caused by an NRAS mutation whose nevus spilus-type GCMN improved on oral selumetinib.<br /> (© 2024 The Author(s). Pediatric Dermatology published by Wiley Periodicals LLC.)
- Subjects :
- Humans
Female
Child
Administration, Oral
Mutation
GTP Phosphohydrolases genetics
Membrane Proteins genetics
Nevus, Pigmented drug therapy
Nevus, Pigmented pathology
Nevus, Pigmented genetics
Nevus, Pigmented congenital
Skin Neoplasms drug therapy
Skin Neoplasms pathology
Skin Neoplasms genetics
Skin Neoplasms congenital
Benzimidazoles therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1525-1470
- Volume :
- 41
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Pediatric dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 38886992
- Full Text :
- https://doi.org/10.1111/pde.15666