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Antioxidant and Anti-Inflammatory Activity of the Ethanolic Extract of Euphorbia Hirta Leaf Extract: An In Vitro and In Silico Study.

Authors :
Praveen G
Krishnamoorthy K
Veeraraghavan VP
Jayaraman S
Source :
Journal of pharmacy & bioallied sciences [J Pharm Bioallied Sci] 2024 Apr; Vol. 16 (Suppl 2), pp. S1304-S1307. Date of Electronic Publication: 2024 Apr 16.
Publication Year :
2024

Abstract

Objectives: This study presents the antioxidant and anti-inflammatory activity of the ethanolic extract of Euphorbia hirta leaf extract.<br />Materials and Methods: The antioxidant and anti-inflammatory activity of the extract was performed by in vitro assay. Our research employs a comprehensive approach combining experimental assays and computational simulations to assess the extract's potential bioactive components and their interactions with key biomolecules.<br />Results: The study's results demonstrated a progressive rise in the percentage of inhibition, which was dependent on the dosage, in both antioxidant and anti-inflammatory activities. This trend was observed for both the extract and the standard, encompassing concentrations ranging from 100 to 500 μg/ml.<br />Conclusion: The results showed that Euphorbia hirta 's possesses antioxidant and anti-inflammatory activity, and this may contribute to a traditional medicinal. The discoveries of this study contribute to a deeper understanding of Euphorbia hirta 's medicinal properties and its potential as a source of natural therapeutic agents.<br />Competing Interests: There are no conflicts of interest.<br /> (Copyright: © 2024 Journal of Pharmacy and Bioallied Sciences.)

Details

Language :
English
ISSN :
0976-4879
Volume :
16
Issue :
Suppl 2
Database :
MEDLINE
Journal :
Journal of pharmacy & bioallied sciences
Publication Type :
Academic Journal
Accession number :
38882735
Full Text :
https://doi.org/10.4103/jpbs.jpbs_591_23