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GD2 Target Antigen and CAR T Cells: Does It Take More Than Two to Tango?
- Source :
-
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Aug 15; Vol. 30 (16), pp. 3361-3363. - Publication Year :
- 2024
-
Abstract
- Over the past decade, chimeric antigen receptor T cells have emerged as a breakthrough cancer therapy in selected hematologic malignancies. Translating the success of this therapy to solid tumors is challenging. In this issue, we discuss strategies potentially useful to increase the chimeric antigen receptor T-cell efficacy in this clinical indication. See related article by Fischer-Riepe et al., p. 3564.<br /> (©2024 American Association for Cancer Research.)
- Subjects :
- Humans
Gangliosides immunology
Antigens, Neoplasm immunology
Receptors, Antigen, T-Cell immunology
Receptors, Antigen, T-Cell metabolism
Hematologic Neoplasms therapy
Hematologic Neoplasms immunology
Receptors, Chimeric Antigen immunology
Immunotherapy, Adoptive methods
T-Lymphocytes immunology
Neoplasms immunology
Neoplasms therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1557-3265
- Volume :
- 30
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Clinical cancer research : an official journal of the American Association for Cancer Research
- Publication Type :
- Academic Journal
- Accession number :
- 38869449
- Full Text :
- https://doi.org/10.1158/1078-0432.CCR-24-0486