Back to Search
Start Over
Reexploring cytomegalovirus serology in allogeneic hematopoietic cell transplantation.
- Source :
-
Current opinion in infectious diseases [Curr Opin Infect Dis] 2024 Aug 01; Vol. 37 (4), pp. 264-269. Date of Electronic Publication: 2024 Jun 10. - Publication Year :
- 2024
-
Abstract
- Purpose of Review: Discuss the recent evidence on cytomegalovirus (CMV) serology in allogeneic hematopoeic cell transplant (HCT) recipients.<br />Recent Findings: Whereas the role CMV-specific cellular mediated immunity has recently emerged as an important factor of CMV DNAemia posttransplant, the value of CMV serology has remained unchanged through decades, associated with donor selection and posttransplant prophylactic and monitoring strategies. In this review, we describe and discuss the emerging reports on the association between the magnitude of pretransplant CMV immunoglobulin G (IgG) titer and the posttransplant incidence of CMV DNAemia, as CMV IgG titer could become an additional tool in CMV risk assessment in the future.<br />Summary: Pretransplant recipient CMV serology may have significant implications in posttransplant CMV reactivation in allogeneic HCT recipients.<br /> (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
- Subjects :
- Humans
Immunoglobulin G blood
Serologic Tests methods
DNA, Viral blood
Cytomegalovirus Infections immunology
Cytomegalovirus Infections prevention & control
Hematopoietic Stem Cell Transplantation adverse effects
Cytomegalovirus immunology
Transplantation, Homologous adverse effects
Antibodies, Viral blood
Subjects
Details
- Language :
- English
- ISSN :
- 1473-6527
- Volume :
- 37
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Current opinion in infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 38861267
- Full Text :
- https://doi.org/10.1097/QCO.0000000000001025