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[Bronchoscopic intervention therapy for pulmonary mucormycosis with main bronchial occlusion: a case report].

Authors :
Wu XX
Wang J
Jin YK
Lin L
Qiu XJ
Zhang J
Wang T
Source :
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases [Zhonghua Jie He He Hu Xi Za Zhi] 2024 Jun 12; Vol. 47 (6), pp. 550-553.
Publication Year :
2024

Abstract

Pulmonary mucormycosis is one of the most common types of mucormycosis. Tracheobronchial pulmonary mucormycosis primarily affects the tracheobronchial tree, causing lesions that can invade the airway mucosa and muscular layer, damaging the cartilage. It is characterised by acute onset, rapid progression, and high mortality rate, making clinical treatment challenging. This article reports the diagnosis and treatment of a patient with pulmonary mucormycosis complicated by left main bronchus occlusion. In addition to systemic treatment, which consisted mainly of an intravenous injection of amphotericin B combined with an oral suspension of posaconazole, the patient underwent multiple bronchoscopic interventions, including local infusion of amphotericin B under endoscopy, balloon dilation and silicone stent placement. After four months of comprehensive treatment, the therapeutic effect was satisfactory. This report demonstrates that bronchoscopic intervention therapy plays an important role in the comprehensive treatment of pulmonary mucormycosis, especially in preventing death from the progression to obstructive pneumonia.

Details

Language :
Chinese
ISSN :
1001-0939
Volume :
47
Issue :
6
Database :
MEDLINE
Journal :
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
Publication Type :
Academic Journal
Accession number :
38858206
Full Text :
https://doi.org/10.3760/cma.j.cn112147-20231124-00338