Back to Search
Start Over
Continuous Flow Electroselenocyclization of Allylamides and Unsaturated Oximes to Selenofunctionalized Oxazolines and Isoxazolines.
Continuous Flow Electroselenocyclization of Allylamides and Unsaturated Oximes to Selenofunctionalized Oxazolines and Isoxazolines.
- Source :
-
ACS organic & inorganic Au [ACS Org Inorg Au] 2024 Mar 11; Vol. 4 (3), pp. 350-355. Date of Electronic Publication: 2024 Mar 11 (Print Publication: 2024). - Publication Year :
- 2024
-
Abstract
- The synthesis of selenofunctionalized oxazolines and isoxazolines from N -allyl benzamides and unsaturated oximes with diselenides was studied by utilizing a continuous flow electrochemical approach. At mild reaction conditions and short reaction times of 10 min product yields of up to 90% were achieved including a scale-up reaction. A broad substrate scope was studied and the reaction was shown to have a wide functional group tolerance.<br />Competing Interests: The authors declare no competing financial interest.<br /> (© 2024 The Authors. Published by American Chemical Society.)
Details
- Language :
- English
- ISSN :
- 2694-247X
- Volume :
- 4
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- ACS organic & inorganic Au
- Publication Type :
- Academic Journal
- Accession number :
- 38855333
- Full Text :
- https://doi.org/10.1021/acsorginorgau.4c00008