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Hospital Healthcare Resource Utilization and Associated Hospital Costs of Patients With Lupus Nephritis in China: A National Administrative Claim Database Study.
- Source :
-
Value in health regional issues [Value Health Reg Issues] 2024 Sep; Vol. 43, pp. 101001. Date of Electronic Publication: 2024 Jun 08. - Publication Year :
- 2024
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Abstract
- Objectives: Assess hospital healthcare resource utilization (HCRU) and associated hospital costs of patients with lupus nephritis (LN) in China and compare these outcomes with a systemic lupus erythematosus (SLE) cohort (SLE with/without LN) as well as exploring the effect of end-stage kidney disease (ESKD).<br />Methods: This retrospective administrative claims-based analysis identified patients with SLE and SLE with LN from China using diagnosis codes and keywords. Patients with LN were subcategorized by presence of ESKD. Outcomes included all-cause and disease-specific HCRU (defined as healthcare visits including inpatient and outpatient visits) and medical costs (in 2022 US dollars).<br />Results: In total, 3645 patients with SLE were included, of whom 404 (11%) had LN. Among those with LN, 142 (35%) had ESKD. Median (interquartile range) all-cause healthcare visits per patient per month (PPPM) was significantly greater for patients with LN (2.08 [4.01]) vs SLE (0.92 [1.64]; P < .0001). Patients with LN and ESKD (3.00 [4.18]) had numerically more all-cause healthcare visits PPPM compared with LN patients without ESKD (1.50 [3.45]). Median all-cause costs PPPM were significantly greater among patients with LN ($287.46 [477.15]) vs SLE ($113.09 [267.39]; P < .0001) and numerically higher for patients with LN and ESKD ($466.29 [958.90]) vs LN without ESKD ($223.50 [319.56]).<br />Conclusions: Chinese patients with LN had greater HCRU and hospital healthcare costs compared with the general SLE cohort. This burden was higher for those with ESKD. These data highlight the substantial HCRU among patients with LN in China, especially those with ESKD, suggesting the need for early diagnosis and timely management of LN to mitigate the economic burden.<br />Competing Interests: Author Disclosures Author disclosure forms can be accessed below in the Supplemental Material section.<br /> (Copyright © 2024 International Society for Health Economics and Outcomes Research. Published by Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Female
China epidemiology
Male
Retrospective Studies
Adult
Middle Aged
Hospital Costs statistics & numerical data
Hospital Costs trends
Kidney Failure, Chronic economics
Kidney Failure, Chronic therapy
Kidney Failure, Chronic epidemiology
Patient Acceptance of Health Care statistics & numerical data
Hospitalization economics
Hospitalization statistics & numerical data
Databases, Factual
Lupus Erythematosus, Systemic economics
Lupus Erythematosus, Systemic therapy
Lupus Erythematosus, Systemic epidemiology
Lupus Nephritis economics
Lupus Nephritis therapy
Lupus Nephritis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 2212-1102
- Volume :
- 43
- Database :
- MEDLINE
- Journal :
- Value in health regional issues
- Publication Type :
- Academic Journal
- Accession number :
- 38850589
- Full Text :
- https://doi.org/10.1016/j.vhri.2024.101001