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A fluorescent probe based on cyclochalcone for detecting peroxynitrite.

Authors :
Liu LH
Shang XZ
Yuan JH
Luo YN
Wang JY
Xue XL
Jiang N
Wang KP
Hu ZQ
Source :
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology [Photochem Photobiol Sci] 2024 Jun; Vol. 23 (6), pp. 1031-1039. Date of Electronic Publication: 2024 Jun 05.
Publication Year :
2024

Abstract

A novel cyclic chalcone fluorescent probe C-PN was synthesized to detect ONOO <superscript>-</superscript> . After reaction with peroxynitrite, the double bond of C-PN in the cyclic chalcone structure was disconnected, which caused the change of intramolecular charge transfer (ICT) effect, emitting blue fluorescence and quenching orange red fluorescence. Visible to the naked eye, the color of the probe solution changed. The probe showed low sensitivity (detection limit = 20.2 nm), short response time (less than 60 s) at low concentration of ONOO <superscript>-</superscript> , good visibility, and good selectivity and stability for ONOO <superscript>-</superscript> .<br /> (© 2024. The Author(s), under exclusive licence to the European Photochemistry Association, European Society for Photobiology.)

Details

Language :
English
ISSN :
1474-9092
Volume :
23
Issue :
6
Database :
MEDLINE
Journal :
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology
Publication Type :
Academic Journal
Accession number :
38839721
Full Text :
https://doi.org/10.1007/s43630-024-00565-y