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Undiagnosed and Untreated Peripheral Complications of Diabetes: Findings from a Pilot Study on Diabetes-Related Foot Diseases (DFD) in Patients with Glycemic Disorders.
- Source :
-
Medical science monitor : international medical journal of experimental and clinical research [Med Sci Monit] 2024 Jun 03; Vol. 30, pp. e944239. Date of Electronic Publication: 2024 Jun 03. - Publication Year :
- 2024
-
Abstract
- BACKGROUND Diabetes-related foot disease (DFD) is a serious complication of diabetes, increasing the risk of amputation. Coimplications are preventable, but most diabetics do not receive proper screening and treatment, despite indications. This study was a pilot screening of diabetes-related foot disease in a group of people with glycemic disorders. MATERIAL AND METHODS We recruited 143 volunteers over 40 years of age. In the final analysis, we included 85 people diagnosed with glycemic disorders (diabetes or prediabetes), for whom we performed a total of 170 foot measurements. We screened for peripheral artery disease using: foot pulse, ankle-brachial index (manual and automatic), toe-brachial index, and transcutaneous oxygen pressure (TcPO2). To screen for diabetic peripheral neuropathy, we used indicators of loss of protective sensation: pressure perception and temperature perception, and plantar pressure distribution. RESULTS A history of diabetes was reported by 26 (30.6%) of the subjects. Disorders of at least 1 foot occurred in 20 (66.7%) subjects with diagnosed diabetes and in 10 (17%) subjects declaring no diabetes. Higher risk and DFD category were correlated with duration of diabetes (r=0.68, p=0.007), glycemic levels (r=0.56, p=0.001), age (r=0.57, p=0.007), and the presence of other diabetes complications. The best predictor of risk in DFD was manual ABI, p=0.001; followed by automatic ABI, p=0.006. CONCLUSIONS Our results showed that peripheral complications of diabetes, such as DFD, often remain undiagnosed and untreated despite the high risk of developing ulcers. There is a need for multi-center screening studies.
- Subjects :
- Humans
Pilot Projects
Male
Female
Middle Aged
Aged
Adult
Ankle Brachial Index
Risk Factors
Diabetes Mellitus, Type 2 complications
Peripheral Arterial Disease diagnosis
Peripheral Arterial Disease complications
Prediabetic State complications
Prediabetic State physiopathology
Diabetic Neuropathies diagnosis
Diabetic Neuropathies physiopathology
Diabetic Neuropathies etiology
Foot physiopathology
Diabetic Foot diagnosis
Diabetic Foot physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 1643-3750
- Volume :
- 30
- Database :
- MEDLINE
- Journal :
- Medical science monitor : international medical journal of experimental and clinical research
- Publication Type :
- Academic Journal
- Accession number :
- 38829832
- Full Text :
- https://doi.org/10.12659/MSM.944239