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Unveiling the Role of Human Papillomavirus in Urogenital Carcinogenesis a Comprehensive Review.

Authors :
Karaoğlan BB
Ürün Y
Source :
Viruses [Viruses] 2024 Apr 25; Vol. 16 (5). Date of Electronic Publication: 2024 Apr 25.
Publication Year :
2024

Abstract

Human papillomavirus (HPV), an oncogenic DNA virus, is the most common sexually transmitted virus and significant public health concern globally. Despite the substantial prevalence of HPV infection among men, routine testing remains elusive due to the lack of approved HPV tests and the complexity of detection methods. Various studies have explored the link between HPV and genitourinary cancers, revealing different associations influenced by geographic variation, histological subtype and methodological differences. These findings underscore the importance of further research to elucidate the role of HPV in male urogenital cancers. This comprehensive review delves into the intricate relationship between HPV and male genitourinary cancers, shedding light on the virus's oncogenic mechanisms and its reported prevalence. A deeper understanding of HPV's implications for male health is essential for advancing public health initiatives and reducing the burden of urogenital cancers worldwide.

Details

Language :
English
ISSN :
1999-4915
Volume :
16
Issue :
5
Database :
MEDLINE
Journal :
Viruses
Publication Type :
Academic Journal
Accession number :
38793549
Full Text :
https://doi.org/10.3390/v16050667