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Blood Group Variations in COVID-19 Convalescent Plasma and Regular Blood Donors: A Comparative Analysis in the Serbian Population.
- Source :
-
Microorganisms [Microorganisms] 2024 Apr 30; Vol. 12 (5). Date of Electronic Publication: 2024 Apr 30. - Publication Year :
- 2024
-
Abstract
- This research explores the association between ABO blood groups and susceptibility to SARS-CoV-2 infection, analyzing Convalescent COVID-19 plasma (CCP) donors ( n = 500) and healthy whole blood donors (BDs) ( n = 9678) during the pandemic (1 May 2020 to 30 April 2021). A comparison is made with pre-pandemic BDs ( n = 11,892) from 1 May 2018 to 30 April 2019. Significant differences in blood group distribution are observed, with blood group A individuals being three times more likely to be CCP donors. Conversely, blood groups B, O, and AB are less associated with CCP donation. Notably, blood group O is more prevalent among regular BDs, suggesting potential resistance to SARS-CoV-2 infection. This study underscores variations in blood group distribution during the pandemic compared to pre-pandemic periods. The findings support previous research indicating a link between blood group antigens and viral susceptibility, including SARS-CoV-2. Understanding these associations has implications for public health strategies, with potential for predicting COVID-19 outcomes and transmission patterns. Further research is crucial to explore molecular and immunological mechanisms, providing valuable insights for targeted preventive strategies and personalized healthcare in managing the impact of COVID-19.
Details
- Language :
- English
- ISSN :
- 2076-2607
- Volume :
- 12
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Microorganisms
- Publication Type :
- Academic Journal
- Accession number :
- 38792740
- Full Text :
- https://doi.org/10.3390/microorganisms12050915