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HEART + score: integrating carotid ultrasound to chest pain assessment in the emergency department.
- Source :
-
CJEM [CJEM] 2024 Jul; Vol. 26 (7), pp. 482-487. Date of Electronic Publication: 2024 May 24. - Publication Year :
- 2024
-
Abstract
- Objectives: The HEART score is a clinical decision tool that stratifies patients into categories of low, moderate, and high-risk of major adverse cardiac events in the emergency department (ED) but cannot identify underlying cardiovascular disease in patients without prior history. The presence of atherosclerosis can easily be detected at the bedside using carotid ultrasound. Plaque quantification is well established, and plaque composition can be assessed using ultrasound grayscale pixel distribution analysis. This study aimed to determine whether carotid plaque burden and/or composition correlated with risk of events and could improve the sensitivity of the HEART score in risk stratifying ED patients with chest pain.<br />Methods: The HEART score was calculated based on history, electrocardiogram, age, risk factors, and initial troponin in patients presenting to the ED with chest pain (n = 321). Focused carotid ultrasound was performed, and maximum plaque height and total plaque area were used to determine plaque burden (quantity). Plaque composition (% blood, fat, muscle, fibrous, calcium-like tissue) was assessed by pixel distribution analysis.<br />Results: Carotid plaque height and area increased with HEART score (p < 0.0001). Carotid plaque % fibrous and % calcium also increased with HEART score. The HEART score had a higher area under the curve (AUC = 0.84) in predicting 30-day events compared to the plaque variables alone (AUCs < 0.70). Integrating plaque quantity into the HEART score slightly increased test sensitivity (62-69%) for 30-day events and reclassified 11 moderate-risk participants to high-risk (score 7-10).<br />Conclusion: Plaque burden with advanced composition features (fibrous and calcium) was associated with increased HEART score. Integrating plaque assessment into the HEART score identified subclinical atherosclerosis in moderate-risk patients.<br /> (© 2024. The Author(s), under exclusive licence to the Canadian Association of Emergency Physicians (CAEP)/ Association Canadienne de Médecine d'Urgence (ACMU).)
- Subjects :
- Humans
Male
Female
Middle Aged
Risk Assessment methods
Aged
Carotid Arteries diagnostic imaging
Ultrasonography methods
Electrocardiography
Plaque, Atherosclerotic diagnostic imaging
Risk Factors
Carotid Artery Diseases diagnostic imaging
Carotid Artery Diseases diagnosis
Carotid Artery Diseases complications
Ultrasonography, Carotid Arteries
Emergency Service, Hospital
Chest Pain etiology
Chest Pain diagnosis
Chest Pain diagnostic imaging
Subjects
Details
- Language :
- English
- ISSN :
- 1481-8043
- Volume :
- 26
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- CJEM
- Publication Type :
- Academic Journal
- Accession number :
- 38789886
- Full Text :
- https://doi.org/10.1007/s43678-024-00711-6