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Fat Grafting and Regenerative Medicine in Burn Care.

Authors :
Alessandri Bonetti M
Piccolo NS
Rubin JP
Egro FM
Source :
Clinics in plastic surgery [Clin Plast Surg] 2024 Jul; Vol. 51 (3), pp. 435-443. Date of Electronic Publication: 2024 Apr 01.
Publication Year :
2024

Abstract

Regenerative therapies such as fat grafting and Platelet Rich Plasma (PRP) have emerged as new options to tackle burn-related injuries and their long-term sequelae. Fat grafting is able to promote wound healing by regulating the inflammatory response, stimulating angiogenesis, favoring the remodeling of the extracellular matrix, and enhancing scar appearance. PRP can enhance wound healing by accelerating stages including hemostasis and re-epithelization. It can improve scar quality and complement fat grafting procedures. Their cost-effectiveness, minimal invasiveness, and promising results observed in the literature have made these tools as therapeutic candidates. The current evidence on fat grafting and PRP in acute and reconstructive burns is described and discussed in this study.<br />Competing Interests: Disclosure The authors have no relevant commercial or financial conflicts of interest or funding sources.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1558-0504
Volume :
51
Issue :
3
Database :
MEDLINE
Journal :
Clinics in plastic surgery
Publication Type :
Academic Journal
Accession number :
38789152
Full Text :
https://doi.org/10.1016/j.cps.2024.02.006