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Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.

Authors :
Wisialowski TA
Ether N
Foley CM
Kleiman R
Koshman Y
Leishman D
Martel E
Nichols JV
Popp J
Rajamani S
Riley S
Rossman EI
Vargas HM
Source :
Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 Jul-Aug; Vol. 128, pp. 107515. Date of Electronic Publication: 2024 May 20.
Publication Year :
2024

Abstract

Competing Interests: Declaration of competing interest None of the authors has any conflicts of interest, other than their employment in commercial biopharmaceutical companies or contract research organizations (CROs). No information is presented in this paper that advocates for or promotes commercial products from any of our organizations.

Details

Language :
English
ISSN :
1873-488X
Volume :
128
Database :
MEDLINE
Journal :
Journal of pharmacological and toxicological methods
Publication Type :
Academic Journal
Accession number :
38777240
Full Text :
https://doi.org/10.1016/j.vascn.2024.107515