Back to Search
Start Over
Formadicins, new monocyclic beta-lactam antibiotics of bacterial origin. II. Isolation, characterization and structures.
- Source :
-
The Journal of antibiotics [J Antibiot (Tokyo)] 1985 Sep; Vol. 38 (9), pp. 1128-40. - Publication Year :
- 1985
-
Abstract
- New monocyclic beta-lactam antibiotics, formadicins A, B, C and D, were isolated from the culture filtrate of Flexibacter alginoliquefaciens sp. nov. YK-49 by various types of column chromatography and preparative reverse-phase HPLC. Their structures were determined by spectroscopic analyses and degradation studies. They have a nocardicin-type skeleton and a formylamino group at the 3- or 12-position. Formadicins A and B each have a D-glucuronide moiety and give formadicins C and D, respectively, upon hydrolysis using beta-D-glucuronidase.
Details
- Language :
- English
- ISSN :
- 0021-8820
- Volume :
- 38
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- The Journal of antibiotics
- Publication Type :
- Academic Journal
- Accession number :
- 3877714
- Full Text :
- https://doi.org/10.7164/antibiotics.38.1128