Whole Spinal Cord FDG Uptake at PET/CT Caused by H3K27-Altered Diffuse Midline Glioma in an Adult Patient.

Authors :: Morin L
Godard F
Aubriot-Lorton MH
Drouet C
Source :: Clinical nuclear medicine [Clin Nucl Med] 2024 Jul 01; Vol. 49 (7), pp. e321-e323. Date of Electronic Publication: 2024 May 21.
Publication Year :: 2024
Abstract: Abstract: Diffuse midline glioma, H3K27-altered, is a relatively new entity, characterized by H3K27M histone mutation. This rare pediatric disease with severe prognosis has recently been identified as a new subtype of diffuse astrocytoma due to major breakthrough in histopathological and molecular characterization of gliomas. We report a case of H3K27-altered diffuse midline glioma in a 30-year-old woman.<br />Competing Interests: Conflicts of interest and sources of funding: none declared.<br /> (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Subjects :: Humans
Female
Adult
Tomography, X-Ray Computed
Multimodal Imaging
Positron Emission Tomography Computed Tomography
Glioma diagnostic imaging
Glioma pathology
Fluorodeoxyglucose F18
Spinal Cord diagnostic imaging
Spinal Cord pathology
Histones metabolism

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