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Epidemiology of Streptococcus pyogenes upper respiratory tract infections in Poland (2003-2017).
- Source :
-
Journal of applied genetics [J Appl Genet] 2024 Sep; Vol. 65 (3), pp. 635-644. Date of Electronic Publication: 2024 May 17. - Publication Year :
- 2024
-
Abstract
- Streptococcus pyogenes (group A Streptococcus, GAS) is a major human pathogen and causes every year over 600 millions upper respiratory tract onfections worldwide. Untreated or repeated infections may lead to post-infectional sequelae such as rheumatic heart disease, a major cause of GAS-mediated mortality. There is no comprehensive, longitudinal analysis of the M type distribution of upper respiratory tract strains isolated in Poland. Single reports describe rather their antibiotic resistance patterns or focus on the invasive isolates. Our goal was to analyse the clonal structure of the upper respiratory tract GAS isolated over multiple years in Poland. Our analysis revealed a clonal structure similar to the ones observed in high-income countries, with M1, M12, M89, M28, and M77 serotypes constituting over 80% of GAS strains. The M77 serotype is a major carrier of erythromycin resistance and is more often correlated with upper respiratory tract infections than other serotypes.<br /> (© 2024. The Author(s).)
- Subjects :
- Poland epidemiology
Humans
Anti-Bacterial Agents pharmacology
Serogroup
Drug Resistance, Bacterial
Female
Male
Microbial Sensitivity Tests
Erythromycin therapeutic use
Adult
Child
Child, Preschool
Streptococcus pyogenes pathogenicity
Streptococcus pyogenes genetics
Streptococcus pyogenes isolation & purification
Streptococcus pyogenes drug effects
Respiratory Tract Infections microbiology
Respiratory Tract Infections epidemiology
Streptococcal Infections epidemiology
Streptococcal Infections microbiology
Subjects
Details
- Language :
- English
- ISSN :
- 2190-3883
- Volume :
- 65
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Journal of applied genetics
- Publication Type :
- Academic Journal
- Accession number :
- 38760644
- Full Text :
- https://doi.org/10.1007/s13353-024-00875-y