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Spontaneous remission of choroidal involvement by chronic myelomonocytic leukemia: a case report.

Authors :
Diral E
Catalano G
Cicinelli MV
Distefano A
Mastaglio S
Vago L
Lupo Stanghellini MT
Bernardi M
Ponzoni M
Ciceri F
Carrabba MG
Source :
Frontiers in oncology [Front Oncol] 2024 May 02; Vol. 14, pp. 1399894. Date of Electronic Publication: 2024 May 02 (Print Publication: 2024).
Publication Year :
2024

Abstract

Chronic myelomonocytic leukemia (CMML) is a rare hematological disorder characterized by variable risk of evolution to acute myeloid leukemia; to date, allogeneic stem cell transplantation is the only curative treatment. We report a case of choroidal involvement in a woman affected by CMML and presenting only with visual impairment. The patient was initially evaluated for an intensive therapeutic approach, but after biopsy the ocular lesion spontaneously regressed. Thus a "watch and wait" strategy was preferred. One year and a half after initial diagnosis, the patient is alive, with stable hematological disease and without any ocular involvement. Therefore, a close, not invasive follow up could be useful to tailor treatment for patients affected by single ocular lesions in CMML.<br />Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision.<br /> (Copyright © 2024 Diral, Catalano, Cicinelli, Distefano, Mastaglio, Vago, Lupo Stanghellini, Bernardi, Ponzoni, Ciceri and Carrabba.)

Details

Language :
English
ISSN :
2234-943X
Volume :
14
Database :
MEDLINE
Journal :
Frontiers in oncology
Publication Type :
Report
Accession number :
38756666
Full Text :
https://doi.org/10.3389/fonc.2024.1399894