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Per- and Polyfluoroalkyl Substances May Be Correlated With Chlamydia trachomatis: Data From the National Health and Nutrition Examination Survey 2003-2016.

Authors :
Taylor BD
Noah AI
Adekanmbi V
Zhang Y
Berenson AB
Source :
Journal of occupational and environmental medicine [J Occup Environ Med] 2024 Sep 01; Vol. 66 (9), pp. 750-756. Date of Electronic Publication: 2024 May 16.
Publication Year :
2024

Abstract

Objective: Per- and polyfluoroalkyl substances (PFAS) alter immune function increasing infectious diseases risk. We examined the relationship between PFAS and chlamydia.<br />Methods: A total of 3965 nonpregnant adults ages 18-39 years from the National Nutrition Examination Survey 2003-2016 cycles were included. Poisson regression with robust error variance estimated the prevalence ratio and 95% confidence intervals for the association between PFAS and chlamydia. A g computation model was used to examine PFAS mixtures and chlamydia.<br />Results: In adjusted age and sex-stratified models, an increase in PFAS mixtures by one quintile was associated with chlamydia in older males and younger females. Associations were not observed before stratification.<br />Conclusions: PFAS exposure associated with higher chlamydia prevalence, but only in stratified models suggesting biological differences by gender and age. However, small sample sizes could have affected the precision of our models.<br />Competing Interests: Conflict of interest: None declared.<br /> (Copyright © 2024 American College of Occupational and Environmental Medicine.)

Details

Language :
English
ISSN :
1536-5948
Volume :
66
Issue :
9
Database :
MEDLINE
Journal :
Journal of occupational and environmental medicine
Publication Type :
Academic Journal
Accession number :
38752649
Full Text :
https://doi.org/10.1097/JOM.0000000000003151