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Construction of a streptavidin-based dual-localized DNAzyme walker for disease biomarker detection.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2024 May 30; Vol. 60 (45), pp. 5848-5851. Date of Electronic Publication: 2024 May 30. - Publication Year :
- 2024
-
Abstract
- A dual-localized DNAzyme walker (dlDW) was constructed by utilizing multiple split DNAzymes with probes, and their substrates are separately localized on streptavidin and AuNPs, serving as walking pedals and tracks, respectively. Based on dlDW, biosensing platform was successfully constructed and showed great potential application in clinical disease diagnosis.
Details
- Language :
- English
- ISSN :
- 1364-548X
- Volume :
- 60
- Issue :
- 45
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 38752318
- Full Text :
- https://doi.org/10.1039/d4cc00912f