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Fusion-harboring mast cells can explain molecular positivity in flow cytometric MRD-negative core-binding factor AML.

Authors :
Cook JA
Lott L
Perry J
Eckel AM
Xu D
Hudson CA
Wells DA
Loken MR
Menssen AJ
Source :
Blood [Blood] 2024 Aug 01; Vol. 144 (5), pp. 581-585.
Publication Year :
2024

Abstract

Abstract: Molecular measurable residual disease can persist in core-binding factor acute myeloid leukemia in otherwise disease-free patients. Utilizing cell sorting followed by fluorescent in situ hybridization, we show that detection is due to mast cells.<br /> (© 2024 American Society of Hematology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.)

Details

Language :
English
ISSN :
1528-0020
Volume :
144
Issue :
5
Database :
MEDLINE
Journal :
Blood
Publication Type :
Academic Journal
Accession number :
38749014
Full Text :
https://doi.org/10.1182/blood.2024024264