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Hypertrophic cardiomyopathy in pregnancy: Nationwide analysis of patients characteristics and outcomes.
- Source :
-
Current problems in cardiology [Curr Probl Cardiol] 2024 Aug; Vol. 49 (8), pp. 102638. Date of Electronic Publication: 2024 May 09. - Publication Year :
- 2024
-
Abstract
- Introduction: Hypertrophic cardiomyopathy (HCM) poses unique challenges in the management of pregnant patients due to the complex interplay of physiological changes of pregnancy. Despite its relatively low prevalence among pregnant women, HCM can significantly impact maternal and fetal outcomes. This study aims to enhance understanding of pregnant patients with HCM and the associated outcomes through a nationwide analysis of patient characteristics and outcomes.<br />Methods: A retrospective analysis was conducted using data obtained from the Agency for Healthcare Research in Quality (AHRQ) Nationwide Inpatient Sample (NIS) database from January 2016 to December 2020. 3,599,855 pregnant patients without HCM and 187 pregnant patients with HCM were identified using International Classification of Disease (ICD) codes, and baseline characteristics, medical comorbidities, and outcomes were compared between the two groups.<br />Results: Significant differences were observed in baseline characteristics, including age distribution, racial composition, and prevalence of systemic organ disease, between pregnant women with and without HCM. Women with HCM had higher odds of experiencing maternal complications, such as acute heart failure and peripartum cardiomyopathy, as well as higher rates of fetal distress and obstetric interventions, including preterm delivery and caesarean section.<br />Conclusion: Comprehensive cardiovascular assessment and risk stratification are essential in pregnant women with HCM to optimize maternal and fetal outcomes. Moreover, disparities in baseline characteristics and outcomes among black pregnant women with HCM highlight the need for a multifactorial approach to addressing pregnancy-related complications.<br />Competing Interests: Declaration of competing interest The authors have no competing interests to declare that are relevant to the content of this article.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Female
Pregnancy
Retrospective Studies
Adult
United States epidemiology
Prevalence
Young Adult
Risk Factors
Cardiomyopathy, Hypertrophic epidemiology
Cardiomyopathy, Hypertrophic therapy
Cardiomyopathy, Hypertrophic diagnosis
Pregnancy Complications, Cardiovascular epidemiology
Pregnancy Complications, Cardiovascular therapy
Pregnancy Complications, Cardiovascular diagnosis
Pregnancy Outcome epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1535-6280
- Volume :
- 49
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Current problems in cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 38734121
- Full Text :
- https://doi.org/10.1016/j.cpcardiol.2024.102638