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Joint-Sparing Resection around the Knee for Osteosarcoma: Long-Term Outcomes of Biologic Reconstruction with Vascularized Fibula Graft Combined with Massive Allograft.

Authors :
Scanferla R
Scolari F
Muratori F
Tamburini A
Delcroix L
Scoccianti G
Beltrami G
Innocenti M
Campanacci DA
Source :
Cancers [Cancers (Basel)] 2024 Apr 26; Vol. 16 (9). Date of Electronic Publication: 2024 Apr 26.
Publication Year :
2024

Abstract

(1) Background: We aim to address the following questions. What was the complication rate of vascularized fibula graft (VFG) combined with massive allograft in patients treated with joint-sparing resection around the knee for a high-grade osteosarcoma? What was the long-term survivorship of VFG free from revision and graft removal? What were the functional results as assessed by the Musculoskeletal Tumor Society (MSTS) score? (2) Methods: 39 patients treated in our unit for osteosarcoma around the knee with intercalary resection and reconstruction with VFG combined with massive allograft were included; 26 patients underwent intercalary tibial resection, while 13 underwent intercalary femoral resection. (3) Results: Mean Follow-Up was 205 months (28 to 424). Complications that required surgery were assessed in requiring surgical revision in 19 patients (49%) after a mean of 31 months (0 to 107), while VFG removal was necessary in three patients (8%). The revision-free survival of the reconstructions was 59% at 5 years and 50% at 10 to 30 years. The overall survival of the reconstructions was 95% at 5 to 15 years and 89% at 20 to 30 years. The mean MSTS score was 29.3 (23 to 30). (4) Conclusions: VFG represents an effective reconstructive option after joint-sparing intercalary resection around the knee for osteosarcoma.

Details

Language :
English
ISSN :
2072-6694
Volume :
16
Issue :
9
Database :
MEDLINE
Journal :
Cancers
Publication Type :
Academic Journal
Accession number :
38730624
Full Text :
https://doi.org/10.3390/cancers16091672