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Comprehensive medication management (CMM): Application of a new pharmaceutical practice in onco-hematology.
- Source :
-
Annales pharmaceutiques francaises [Ann Pharm Fr] 2024 Sep; Vol. 82 (5), pp. 873-885. Date of Electronic Publication: 2024 May 08. - Publication Year :
- 2024
-
Abstract
- The integration of a large number of drugs, such as antineoplastic agents and cancer-related supportive care drugs, into the management of cancer patients exposes them to an increased number of drug-related problems (DRP). Clinical pharmacists contribute to drug management by actively intervening in detected DRP. The aim of this study is to assess the impact of the applying a clinical pharmacist-driven comprehensive medication management (CMM) service to onco-hematology patients. This prospective interventional study was carried out over six-month duration, specifically from November 06, 2022 to April 5, 2023 in the oncology and hematology departments of the EHU Oran. The adherence to treatment was evaluated using the 8-item Morisky Medication Adherence Scale (MMAS). Whereas data related to the patient's general condition and medication history was assessed using the Pharmaceutical Care Network Europe (PCNE) Classification for Drug-Related Problems V9.1. Among the 130 patients included in the study, a total of 879 DRP were identified, with a mean of 6.78 (±1.72) DRP/patient, half of which were related to efficacy (51%). Almost half of our sample (44.6%) did not adhere to their treatment. The most frequent cause of DRP, accounting for (19.9%) of the cases, was the inappropriate administration by a health professional. A total of 875 pharmaceuticals interventions (PI) were proposed, 67.2% of which were focused at the drug level. The PI acceptance rate was 94.1%. The integration of CMM services in onco-hematology played an important role in optimizing dosing regimen and treatment administration methods, as well as preventing iatropathology in the management of cancer patients.<br /> (Copyright © 2024 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.)
- Subjects :
- Humans
Male
Female
Middle Aged
Aged
Prospective Studies
Adult
Pharmacy Service, Hospital organization & administration
Medication Therapy Management
Neoplasms drug therapy
Aged, 80 and over
Hematology
Medical Oncology
Drug-Related Side Effects and Adverse Reactions prevention & control
Pharmacists
Antineoplastic Agents therapeutic use
Medication Adherence
Subjects
Details
- Language :
- English
- ISSN :
- 0003-4509
- Volume :
- 82
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Annales pharmaceutiques francaises
- Publication Type :
- Academic Journal
- Accession number :
- 38729518
- Full Text :
- https://doi.org/10.1016/j.pharma.2024.05.001