Effects of Plasmapheresis on Serum Lithium Levels in an ICU Patient with Bipolar Disorder: A Case Study.

Authors :: Lien TNT
Mohamed SMM
van den Bogaard B
Touw DJ
Franssen EJF
Source :: Therapeutic drug monitoring [Ther Drug Monit] 2024 Jun 01; Vol. 46 (3), pp. 281-284.
Publication Year :: 2024
Abstract: Abstract: This is a case description of a patient with bipolar disorder undergoing lithium therapy who received plasmapheresis for neuromyelitis optica spectrum disorder. Plasmapheresis resulted in lower and subtherapeutic serum lithium levels. Using therapeutic drug monitoring, a dose escalation of 80% was necessary to maintain therapeutic serum lithium levels. This underscores the importance of individualized therapy through therapeutic drug monitoring.<br />Competing Interests: The authors declare no conflict of interest.<br /> (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)

Subjects :: Humans
Antimanic Agents therapeutic use
Antimanic Agents blood
Intensive Care Units
Lithium blood
Lithium therapeutic use
Bipolar Disorder therapy
Bipolar Disorder blood
Drug Monitoring methods
Neuromyelitis Optica therapy
Neuromyelitis Optica blood
Plasmapheresis methods

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