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Regional anesthesia in neonates with cleft lip and palate: Retrospective study.
- Source :
-
International journal of pediatric otorhinolaryngology [Int J Pediatr Otorhinolaryngol] 2024 May; Vol. 180, pp. 111965. Date of Electronic Publication: 2024 May 04. - Publication Year :
- 2024
-
Abstract
- Background: Orofacial clefts are the most common congenital abnormalities. Cleft lip reconstruction is performed mostly in 3 months of life including the neonatal period. The consumption of opioids during anesthesia is one of the monitored parameters of anesthesia safety. We investigated the effect of using an infraorbital nerve block for reducing opioid consumption during cleft lip surgery in neonates.<br />Patients/methods: Overall, 100 patients who underwent primary cleft lip surgery in neonatal age between 2018 and 2021 were included in the study. The primary outcome was to compare opioid requirements during cleft lip surgery with and without using regional anesthesia. Secondary outcomes included a first oral intake from surgery between neonates with and without regional anesthesia and complications rate of infraorbital nerve block.<br />Results: Data from 100 patients (46 patients with and 64 without regional anesthesia) were retrospectively analyzed and classified into two groups according to whether regional anesthesia during neonatal cleft lip surgery had been performed or not. The use of infraorbital block was found to be positively correlated with lower doses of opioids used during the general anesthesia for the surgery (mean 0.48 μg/kg vs 0.29 μg/kg, p < 0.05). The postoperative course was evaluated based on the interval from surgery to first oral intake which was statistically insignificant shorter (p = 0.16) in the group of patients using regional anesthesia. No complications were recorded in the group of patients with regional anesthesia.<br />Conclusions: Regional anesthesia is associated with reduced opioid consumption during anesthesia thereby increasing the safety of anesthesia in neonates.<br />Gov Identifier: NCT06067854https://clinicaltrials.gov/study/NCT06067854?cond=NCT06067854&rank=1.<br />Competing Interests: Declaration of competing interest The authors declare no conflicts of interest.<br /> (Copyright © 2024 Elsevier B.V. All rights reserved.)
- Subjects :
- Humans
Retrospective Studies
Male
Female
Infant, Newborn
Pain, Postoperative drug therapy
Pain, Postoperative prevention & control
Plastic Surgery Procedures methods
Plastic Surgery Procedures adverse effects
Cleft Lip surgery
Cleft Palate surgery
Anesthesia, Conduction methods
Nerve Block methods
Analgesics, Opioid therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 1872-8464
- Volume :
- 180
- Database :
- MEDLINE
- Journal :
- International journal of pediatric otorhinolaryngology
- Publication Type :
- Academic Journal
- Accession number :
- 38718430
- Full Text :
- https://doi.org/10.1016/j.ijporl.2024.111965