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Glycoconjugates: Advances in modern medicines and human health.

Authors :
Chettri D
Chirania M
Boro D
Verma AK
Source :
Life sciences [Life Sci] 2024 Jul 01; Vol. 348, pp. 122689. Date of Electronic Publication: 2024 May 04.
Publication Year :
2024

Abstract

Glycans and their glycoconjugates are complex biomolecules that are crucial for various biological processes. Glycoconjugates are found in all domains of life. They are covalently linked to key biomolecules such as proteins and lipids to play a pivotal role in cell signaling, adhesion, and recognition. The diversity of glycan structures and the associated complexity of glycoconjugates is the reason for their role in intricate biosynthetic pathways. Glycoconjugates play an important role in various diseases where they are actively involved in the immune response as well as in the pathogenicity of infectious diseases. In addition, various autoimmune diseases have been linked to glycosylation defects of different biomolecules, making them an important molecule in the field of medicine. The glycoconjugates have been explored for the development of therapeutics and vaccines, representing a breakthrough in medical science. They also hold significance in research studies to understand the mechanisms behind various biological processes. Finally, glycoconjugates have found an emerging role in various industrial and environmental applications which have been discussed here.<br />Competing Interests: Declaration of competing interest The author declares that the research was conducted without any commercial or financial relationships that could be construed as a potential conflict of interest.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)

Details

Language :
English
ISSN :
1879-0631
Volume :
348
Database :
MEDLINE
Journal :
Life sciences
Publication Type :
Academic Journal
Accession number :
38710281
Full Text :
https://doi.org/10.1016/j.lfs.2024.122689