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Impact of fundamental components of the Mediterranean diet on the microbiota composition in blood pressure regulation.

Authors :
Zambrano AK
Cadena-Ullauri S
Ruiz-Pozo VA
Tamayo-Trujillo R
Paz-Cruz E
Guevara-Ramírez P
Frias-Toral E
Simancas-Racines D
Source :
Journal of translational medicine [J Transl Med] 2024 May 03; Vol. 22 (1), pp. 417. Date of Electronic Publication: 2024 May 03.
Publication Year :
2024

Abstract

Background: The Mediterranean diet (MedDiet) is a widely studied dietary pattern reflecting the culinary traditions of Mediterranean regions. High adherence to MedDiet correlates with reduced blood pressure and lower cardiovascular disease (CVD) incidence and mortality. Furthermore, microbiota, influenced by diet, plays a crucial role in cardiovascular health, and dysbiosis in CVD patients suggests the possible beneficial effects of microbiota modulation on blood pressure. The MedDiet, rich in fiber and polyphenols, shapes a distinct microbiota, associated with higher biodiversity and positive health effects. The review aims to describe how various Mediterranean diet components impact gut microbiota, influencing blood pressure dynamics.<br />Main Body: The MedDiet promotes gut health and blood pressure regulation through its various components. For instance, whole grains promote a healthy gut microbiota given that they act as substrates leading to the production of short-chain fatty acids (SCFAs) that can modulate the immune response, preserve gut barrier integrity, and regulate energy metabolism. Other components of the MedDiet, including olive oil, fuits, vegetables, red wine, fish, and lean proteins, have also been associated with blood pressure and gut microbiota regulation.<br />Conclusion: The MedDiet is a dietary approach that offers several health benefits in terms of cardiovascular disease management and its associated risk factors, including hypertension. Furthermore, the intake of MedDiet components promote a favorable gut microbiota environment, which, in turn, has been shown that aids in other physiological processes like blood pressure regulation.<br /> (© 2024. The Author(s).)

Details

Language :
English
ISSN :
1479-5876
Volume :
22
Issue :
1
Database :
MEDLINE
Journal :
Journal of translational medicine
Publication Type :
Academic Journal
Accession number :
38702795
Full Text :
https://doi.org/10.1186/s12967-024-05175-x