Supplementation with NAD+ and its precursors: A rescue of female reproductive diseases.

Nicotinamide adenine dinucleotide (NAD ⁺ ) is an essential coenzyme involved in many pathophysiological processes. Supplementation with NAD ⁺ and its precursors has been demonstrated as an emerging therapeutic strategy for the diseases. NAD ⁺ also plays an important role in the reproductive system. Here, we summarize the function of NAD ⁺ in various reproductive diseases and review the application of NAD ⁺ and its precursors in the preservation of reproductive capacity and the prevention of embryonic malformations. It is shown that NAD ⁺ shows good promise as a therapeutic approach for saving reproductive capacity.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2024 The Authors.)