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Accelerometer-measured physical activity and sedentary behaviour are associated with C-reactive protein in US adults who get insufficient sleep: A threshold and isotemporal substitution effect analysis.
- Source :
-
Journal of sports sciences [J Sports Sci] 2024 Mar; Vol. 42 (6), pp. 527-536. Date of Electronic Publication: 2024 May 02. - Publication Year :
- 2024
-
Abstract
- This study aimed to investigate the association between physical activity, sedentary behaviour and chronic inflammation in short sleep adults. The study included 2,113 NHANES participants with self-reported insufficient sleep. C-reactive protein (CRP) was used as the inflammatory biomarker. Physical activity and sedentary behaviour were objectively measured by accelerometers. Weighted regression model, two - piecewise linear regression model, and restricted cubic splines were applied to evaluate associations mentioned above. An isotemporal substitution model was used to assess the modelled effects of replacing sedentary time (ST) with moderate-to-vigorous levels of physical activity (MVPA) or light physical activity (LPA). After adjusting for potential confounding factors, higher levels of ST and lower levels of LPA or MVPA were associated with higher CRP levels. Isotemporal substitution analysis indicated that replacing 30 minutes of ST with 30 minutes of MVPA was associated with a significant decrease in CRP levels. Saturation analysis suggested that the association between MVPA and CRP may plateau at over 20 minutes of MVPA per day. Findings of this study provides insight into the potential benefits of replacing ST with MVPA. This study also suggests that increasing MVPA beyond a certain point may not provide additional anti-inflammatory benefits in a short sleep population.
- Subjects :
- Humans
Male
Female
Middle Aged
Adult
United States
Inflammation blood
Sleep Deprivation blood
Sleep Deprivation physiopathology
Nutrition Surveys
Cross-Sectional Studies
Aged
Time Factors
C-Reactive Protein metabolism
C-Reactive Protein analysis
Sedentary Behavior
Accelerometry
Exercise physiology
Biomarkers blood
Subjects
Details
- Language :
- English
- ISSN :
- 1466-447X
- Volume :
- 42
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of sports sciences
- Publication Type :
- Academic Journal
- Accession number :
- 38695324
- Full Text :
- https://doi.org/10.1080/02640414.2024.2348906