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Perioperative analgesic effects of the erector spinae plane block with bupivacaine or bupivacaine-dexmedetomidine in dogs undergoing hemilaminectomy: A randomized controlled trial.
- Source :
-
The Canadian veterinary journal = La revue veterinaire canadienne [Can Vet J] 2024 May; Vol. 65 (5), pp. 473-480. - Publication Year :
- 2024
-
Abstract
- Objective: To compare the perioperative opioid requirements among dogs receiving an erector spinae plane (ESP) block with bupivacaine, with or without dexmedetomidine, and a control group.<br />Animals and Procedure: Thirty client-owned, healthy adult dogs undergoing hemilaminectomy were included in this randomized, prospective, blinded clinical study. Dogs were randomly assigned to 1 of 3 treatment groups: Group B, ESP block with bupivacaine; Group BD, ESP block with bupivacaine and dexmedetomidine; and Group C, control. Rescue intra- and postoperative analgesia consisted of fentanyl and methadone, respectively. Postoperative pain was evaluated using the short form of the Glasgow Composite Measure Pain Scale (CMPS-SF).<br />Results: In Group BD, 0/10 dogs required intraoperative fentanyl, compared to 9/10 in Group C ( P < 0.001), whereas 1/10 required postoperative methadone, compared to 9/10 in Group B ( P = 0.003) and 10/10 in Group C ( P < 0.001). The total amount of intraoperative fentanyl (μg/kg) was 0 (0 to 4) in Group B and 0 (0 to 0) in BD, compared to 6 (0 to 8) in C ( P = 0.004 and P < 0.001, respectively). Postoperative methadone (mg/kg) required during the first 12 h was 0.5 (0 to 1.4) in Group B ( P = 0.003) and 0 (0 to 0) in BD ( P < 0.001), compared to C ( P = 0.003 and P < 0.001, respectively).<br />Conclusion: An ESP block with bupivacaine, with or without dexmedetomidine, was associated with a reduction in perioperative opioid consumption and provided effective acute pain control.<br /> (Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.)
- Subjects :
- Animals
Dogs
Male
Female
Analgesics, Opioid administration & dosage
Analgesics, Opioid therapeutic use
Fentanyl administration & dosage
Fentanyl pharmacology
Fentanyl therapeutic use
Dog Diseases surgery
Dog Diseases drug therapy
Prospective Studies
Bupivacaine administration & dosage
Bupivacaine therapeutic use
Dexmedetomidine administration & dosage
Dexmedetomidine pharmacology
Pain, Postoperative veterinary
Pain, Postoperative prevention & control
Pain, Postoperative drug therapy
Nerve Block veterinary
Anesthetics, Local administration & dosage
Anesthetics, Local therapeutic use
Laminectomy veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 0008-5286
- Volume :
- 65
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The Canadian veterinary journal = La revue veterinaire canadienne
- Publication Type :
- Academic Journal
- Accession number :
- 38694736