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Does Formalin Disinfection Reduce Bacterial Colonization of Biopsy Needle? A Prospective Study.
- Source :
-
Urology [Urology] 2024 Jul; Vol. 189, pp. 87-93. Date of Electronic Publication: 2024 Apr 29. - Publication Year :
- 2024
-
Abstract
- Objective: To investigate the efficacy of formalin disinfection of the needle tip in transrectal prostate biopsy (TRB) procedure to reduce infectious complications. The primary aim is to assess the impact of formalin on bacterial contamination of biopsy needle tips and its association with post-biopsy infective events.<br />Materials and Methods: We have employed a bacterial culture-based observational cohort design in this study. Two groups, formalin disinfection and non-formalin group, both underwent systematic 12-core TRB. In the formalin group, the biopsy needle tip was immersed in 10% formalin solution after each core, while in the non-formalin group, no formalin solution immersion was used. The primary outcomes include bacterial growth on biopsy needle tips and post-biopsy infective events.<br />Results: Formalin disinfection significantly reduced bacterial growth on needle tips (P <.001). The formalin group had no post-biopsy infections or sepsis, while the non-formalin group experienced a 7.5% infective event rate after TRB.<br />Conclusion: Formalin disinfection of biopsy needle tip significantly reduces bacterial growth on biopsy needle and urinary tract infectious complications developed secondary to TRB. Further multicenter randomized controlled studies with larger cohorts are warranted to validate and establish formalin disinfection as a routine practice in TRB procedures.<br />Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.<br /> (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Subjects :
- Humans
Male
Prospective Studies
Biopsy, Needle methods
Biopsy, Needle instrumentation
Biopsy, Needle adverse effects
Aged
Middle Aged
Disinfectants pharmacology
Equipment Contamination prevention & control
Prostate pathology
Prostate microbiology
Needles microbiology
Urinary Tract Infections prevention & control
Formaldehyde pharmacology
Disinfection methods
Subjects
Details
- Language :
- English
- ISSN :
- 1527-9995
- Volume :
- 189
- Database :
- MEDLINE
- Journal :
- Urology
- Publication Type :
- Academic Journal
- Accession number :
- 38692495
- Full Text :
- https://doi.org/10.1016/j.urology.2024.04.017