Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease.

Authors :: Sharma A
Selukar S
Bi Y
Merlocco A
Morin CE
Goode C
Rai P
Towbin JA
Hankins JS
Gottschalk S
Triplett B
Johnson JN
Source :: Blood [Blood] 2024 Aug 08; Vol. 144 (6), pp. 672-675.
Publication Year :: 2024
Abstract: Abstract: Serial cardiovascular magnetic resonance evaluation of children and young adults with SCD who underwent hematopoietic cell transplantation showed mean ECV, representing diffuse myocardial fibrosis, decreased 3.4% from baseline to 12 months posttransplantation. This trial was registered at www.clinicaltrials.gov as #NCT04362293.<br /> (© 2024 American Society of Hematology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.)

Subjects :: Humans
Male
Female
Adolescent
Child
Young Adult
Cardiomyopathies etiology
Cardiomyopathies therapy
Cardiomyopathies pathology
Adult
Myocardium pathology
Magnetic Resonance Imaging
Child, Preschool
Anemia, Sickle Cell therapy
Anemia, Sickle Cell pathology
Anemia, Sickle Cell complications
Hematopoietic Stem Cell Transplantation
Fibrosis

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