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Essential oil from Piper tuberculatum Jacq. (Piperaceae) and its majority compound β-caryophyllene: mechanism of larvicidal action against Aedes aegypti (Diptera: Culicidae) and selective toxicity.
- Source :
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Environmental science and pollution research international [Environ Sci Pollut Res Int] 2024 May; Vol. 31 (23), pp. 33454-33463. Date of Electronic Publication: 2024 Apr 29. - Publication Year :
- 2024
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Abstract
- Synthetic insecticides have been the primary approach in controlling Aedes aegypti; however, their indiscriminate use has led to the development of resistance and toxicity to non-target animals. In contrast, essential oils (EOs) are alternatives for vector control. This study investigated the mechanism of larvicidal action of the EO and β-caryophyllene from Piper tuberculatum against A. aegypti larvae, as well as evaluated the toxicity of both on non-target animals. The EO extracted from P. tuberculatum leaves was majority constituted of β-caryophyllene (54.8%). Both demonstrated larvicidal activity (LC <subscript>50</subscript> of 48.61 and 57.20 ppm, p < 0.05), acetylcholinesterase inhibition (IC <subscript>50</subscript> of 57.78 and 71.97 ppm), and an increase in the production of reactive oxygen and nitrogen species in larvae after exposure to the EO and β-caryophyllene. Furthermore, EO and β-caryophyllene demonstrate no toxicity to non-target animals Toxorhynchites haemorrhoidalis, Anisops bouvieri, and Diplonychus indicus (100% of survival rate), while the insecticide α-cypermethrin was highly toxic (100% of death). The results demonstrate that the EO from P. tuberculatum and β-caryophyllene are important larvicidal agents.<br /> (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Details
- Language :
- English
- ISSN :
- 1614-7499
- Volume :
- 31
- Issue :
- 23
- Database :
- MEDLINE
- Journal :
- Environmental science and pollution research international
- Publication Type :
- Academic Journal
- Accession number :
- 38684608
- Full Text :
- https://doi.org/10.1007/s11356-024-33416-5