Performance of Urinalysis Parameters in Predicting Urinary Tract Infection: Does One Size Fit All?

In a multihospital cohort study of 3392 patients, positive urinalysis parameters had poor positive predictive value for diagnosing urinary tract infection (UTI). Combined urinalysis parameters (pyuria or nitrite) performed better than pyuria alone for ruling out UTI. However, performance of all urinalysis parameters was poor in older women.
Competing Interests: Potential conflicts of interest. S. D. A. and R. N. report support from the Centers for Disease Control and Prevention (SHEPheRD 75D30121D12733-D5-E003) and the Duke Claude D. Pepper Older Americans Independence Center (National Institute on Aging grant number P30AG028716). S. D. A. also reports support from the Society for Healthcare Epidemiology of America, as well as consulting fees from Locus Biosciences (ended), Sysmex America (ended), GlaxoSmithKline, bioMérieux, and the Infectious Diseases Society of America.. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.
(© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)