Severe A(H1N1)pdm09 influenza acute encephalopathy outbreak in children in Tuscany, Italy, December 2023 to January 2024.

Authors :: Bartolini L
Ricci S
Azzari C
Moriondo M
Nieddu F
L'Erario M
Ricci Z
Simonini G
Mortilla M
Indolfi G
Montagnani C
Chiappini E
Galli L
Guerrini R
Source :: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin [Euro Surveill] 2024 Apr; Vol. 29 (17).
Publication Year :: 2024
Abstract: A severe outbreak of influenza A(H1N1pdm09) infection in seven children (median age: 52 months) occurred between December 2023 and January 2024 in Tuscany, Italy. Clinical presentation ranged from milder encephalopathy to acute necrotizing encephalopathy (ANE) with coma and multiorgan failure; one child died. This report raises awareness for clinicians to identify and treat early acute encephalopathy caused by H1N1 influenza and serves as a reminder of severe presentations of influenza in young children and the importance of vaccination.

Subjects :: Humans
Italy epidemiology
Child, Preschool
Male
Female
Child
Infant
Brain Diseases epidemiology
Brain Diseases virology
Influenza, Human epidemiology
Influenza, Human diagnosis
Influenza, Human virology
Influenza A Virus, H1N1 Subtype isolation & purification
Disease Outbreaks

Language :: English
ISSN :: 1560-7917
Volume :: 29
Issue :: 17
Database :: MEDLINE
Journal :: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
Publication Type :: Academic Journal
Accession number :: 38666399
Full Text :: https://doi.org/10.2807/1560-7917.ES.2024.29.17.2400199

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