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[The role of exposure to airborne pollutants in the workplace on the prevalence and severity of chronic respiratory disease in Italy].
- Source :
-
Epidemiologia e prevenzione [Epidemiol Prev] 2023 Nov-Dec; Vol. 47 (6), pp. 56-66. - Publication Year :
- 2023
-
Abstract
- Objectives: occupational exposure to vapours, gases, dusts and fumes (VGDF) plays an important role in the development and exacerbation of respiratory diseases. The aim of this study is to evaluate the possible association of occupational exposure to airborne pollutants and chronic respiratory diseases.<br />Design: multicase-control study.<br />Setting and Participants: cases of chronic respiratory diseases and controls from the Italian multicentric study Gene Environment Interaction in Respiratory Diseases (GEIRD).<br />Main Outcome Measures: the occurrence of rhinitis, asthma, chronic bronchitis/chronic obstructive pulmonary disease (COPD), asthma severity, spirometry data, exhaled nitric oxide (FeNO) were examined in relation to chronic and acute occupational exposures to airborne pollutants using multiple regression models.<br />Results: 2,943 subjects were enrolled in the study. Regularm exposure to VGDF was associated with a higher prevalence of chronic bronchitis/COPD (OR 1.40, 95%CI 0.98-1.99), especially in those also having asthma (OR 1.80, 95%CI 1.14-2.85), a lower prevalence of remittent asthma (OR 0.53, 95%CI 0.29-0.96) and, in those with asthma, an increased activity of the disease (severity score) (OR 1.77, 95%CI 1.20-2.60). No associations were observed between occupational exposure and prevalence of rhinitis, spirometry and FeNO data. Finally, an association was found between acute exposure to airborne pollutants (occupational and non-occupational) and the respiratory diseases investigated, in particular active asthma and asthma associated chronic bronchitis/BPCO.<br />Conclusions: these data confirm a significant role of occupational exposure to airborne pollutants on respiratory health, underlying the importance of workplace exposure prevention, in particular for more susceptible subjects, as those with respiratory diseases.
- Subjects :
- Humans
Prevalence
Risk Factors
Italy epidemiology
Workplace
Gases
Bronchitis, Chronic epidemiology
Bronchitis, Chronic etiology
Environmental Pollutants
Occupational Diseases epidemiology
Occupational Diseases etiology
Pulmonary Disease, Chronic Obstructive epidemiology
Pulmonary Disease, Chronic Obstructive etiology
Asthma epidemiology
Asthma etiology
Occupational Exposure adverse effects
Respiration Disorders
Rhinitis
Subjects
Details
- Language :
- Italian
- ISSN :
- 1120-9763
- Volume :
- 47
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Epidemiologia e prevenzione
- Publication Type :
- Academic Journal
- Accession number :
- 38639301
- Full Text :
- https://doi.org/10.19191/EP23.6.S3.008